Simbrinza Ophthalmic Suspension (Brinzolamide/Brimonidine Tartrate) is an eye drop used to decrease pressure inside the eye. Simbrinza can be used to treat open-angle glaucoma or ocular hypertension.

Please read the instructions carefully and follow your doctor’s directions

• Do not use while wearing contact lenses
• Wait 15 minutes after using Simbrinza before putting contact lenses back on
• Wash your hands before using Simbrinza eye drops
• Shake before using
• Use only the number of drops prescribed by your doctor
• For more than one drop, wait five minutes between drops

Make sure your doctor is notified if you have:

• Kidney disease
• Liver disease
• Congestive heart failure
• Coronary artery disease
• A history of stroke or blood clot
• High or low blood pressure
• Circulation problems
• Narrow-angle glaucoma
• An allergy to sulfa drugs, brimonidine, or brinzolamide

Common side effects of Simbrinza include:

• Blurred vision
• Mild itching and redness in the eyes
• Dry mouth

Stop using Simbrinza and talk to your doctor if you experience:

• Sudden liver failure, characterized by nausea, vomiting, itching, fatigue, appetite loss, dark urine, jaundice, confusion, and rapid weight gain.
• Bone marrow suppression, characterized by sudden fever, chills, mouth sores, swollen gums, sore throat, trouble swallowing, light-headedness, rapid heart rate, and difficulty focusing.
• Severe skin reaction, characterized by fever, sore throat, face swelling, burning eyes, purple rash, skin pain, blistering or peeling.

What is brimonidine tartrate ophthalmic solution used for?

This eye drop solution is used for reducing the amount of fluid in the eye. As a result, the pressure inside the eye can be relieved.

What is brimonidine tartrate?

Brimonidine tartrate is the tartrate salt form of brimonidine, which is an alpha-2 adrenergic receptor agonist. It acts to constrict blood vessels within the eyes, decreasing the production of eye fluid and improving the eye’s ability to expel fluids.